GDP volatility is a fundamental development concern given its undeniable connections to lack of development. The negative link between short-term fluctuations and long-term growth not only signifies the importance of understanding this relationship but also stresses the need to identify its structural determinants. This macro-panel study examines the determinants of GDP fluctuations across selected South Asian countries using a panel framework with modern non-stationary econometric techniques. The study identifies key structural, policy, and external factors driving GDP volatility in the South Asian context, with findings relevant to the design of macroeconomic stabilisation policy and structural reform agendas.